{"id":6137,"date":"2020-02-05T13:09:32","date_gmt":"2020-02-05T05:09:32","guid":{"rendered":"http:\/\/www.brofive.org\/?p=6137"},"modified":"2021-07-30T23:41:04","modified_gmt":"2021-07-30T15:41:04","slug":"%e7%9f%b3%e6%ad%a3%e4%b8%bd%e4%ba%8b%e4%bb%b6%e7%9a%84%e5%89%8d%e5%90%8e%e6%95%b4%e7%90%86%ef%bc%8c%e5%8f%8a%e6%ad%a6%e5%b0%8f%e5%8d%8e%e5%8d%9a%e5%a3%ab%e6%89%93%e8%84%b8%e5%a5%b9","status":"publish","type":"post","link":"http:\/\/www.brofive.net\/?p=6137","title":{"rendered":"[\u8f6c]\u77f3\u6b63\u4e3d\u4e8b\u4ef6\u7684\u524d\u540e\u6574\u7406\uff0c\u53ca\u6b66\u5c0f\u534e\u535a\u58eb\u6253\u8138\u5979\u3002\u5b9e\u4e3a\u7f8e\u5e1d\u4e0b\u6bd2\uff01"},"content":{"rendered":"

\u301020210730\u8865\u3011\u7ecf\u8fc7\u610f\u5927\u5229\u3001\u7f8e\u56fd\u79d1\u5b66\u5bb6\u7814\u7a76\u8bba\u8bc1\uff0c\u75c5\u6bd2\u6765\u6e90\u4e8e\u7f8e\u56fd\u5fb7\u7279\u91cc\u514b\u5821\u5b9e\u9a8c\u5ba4\uff0c\u5e76\u4e14\u79cd\u79cd\u8bc1\u636e\u5747\u6307\u5411\u8fd9\u4e2a\u5b9e\u9a8c\u5ba4\uff01\uff01\u7f8e\u5e1d\u7ed9\u5168\u4e16\u754c\u4e0b\u6bd2\u7684\u8bc1\u636e\u5b9e\u9524\u4e86\u3002<\/span><\/h3>\n

http:\/\/www.brofive.net\/?p=8904<\/a><\/h3>\n

\u301020210530\u8865\u3011\u73b0\u5728\u8fd4\u8fc7\u53bb\u770b\u4e00\u5e74\u591a\u524d\u7684\u8fd9\u7bc7\u6587\u7ae0\uff0c\u5e94\u8be5\u8bf4\u8fd9\u6b21\u75c5\u6bd2\u6765\u81ea\u6d77\u5916\uff0c\u6765\u81ea\u7f8e\u56fd\u7684\u53ef\u80fd\u6027\u6700\u5927\uff0c\u4e4b\u6240\u4ee5\u53d1\u751f\u5728\u6b66\u6c49\uff0c\u5e76\u4e0d\u662f\u56e0\u4e3a\u8fd9\u91cc\u9762\u6709\u4e2a\u75c5\u6bd2\u7814\u7a76\u6240\uff0c\u800c\u662f\u6765\u81ea\u519b\u8fd0\u4f1a\u7684\u7f8e\u56fd\u8fd0\u52a8\u5458\u3002\u90a3\u4e48\u4e3a\u4ec0\u4e48\u548c\u8fd9\u4e2a\u6d77\u9c9c\u5e02\u573a\u6709\u5173\u7cfb\u5462\uff1f\u6211\u7406\u89e3\u65b0\u51a0\u75c5\u6bd2\u5c31\u5982\u540c\u540e\u6765\u90a3\u6837\u968f\u7740\u6d77\u9c9c\u5feb\u9012\u6765\u5230\u4e2d\u56fd\u3002\u8fd9\u662f\u4e00\u6b21\u591a\u8def\u5f84\u4f20\u64ad\uff0c\u662f\u7f8e\u5e1d\u7ed9\u6211\u5927\u5510\u4e0b\u6bd2\uff01\uff01<\/span><\/h3>\n

\u301020200422\u8865\u3011\u8fd9\u4e48\u591a\u5929\u8fc7\u540e\uff0c\u53cd\u8fc7\u5934\u6765\u770b\u8fd9\u7bc7\u6587\u7ae0\uff0c\u591a\u6570\u4eba\u4f1a\u8ba4\u8bc6\u5230\uff1a<\/span><\/h3>\n

\uff081\uff09\u867d\u7136\u4e8b\u60c5\u771f\u76f8\u672a\u77e5\uff0c\u4f46\u662f\u7f8e\u56fd\u57fa\u56e0\u6b66\u5668\u7684\u5acc\u7591\u66f4\u5927\uff0c\u56e0\u4e3a\u7f8e\u56fd\u624d\u662f\u65b0\u51a0\u76840\u53f7\u75c5\u4eba\u53d1\u6e90\u5730\u3002<\/span><\/h3>\n

\uff082\uff09\u8fd9\u6b21\u5bf9\u75c5\u6bd2\u7814\u7a76\u4eba\u5458\u7684\u8b66\u793a\u66f4\u5927\uff1a\u4eba\u7c7b\u57fa\u56e0\u3001\u75c5\u6bd2\u7814\u7a76\uff0c\u4e0d\u80fd\u8131\u79bb\u4f26\u7406\u3001\u4e0d\u80fd\u8131\u79bb\u5b89\u5168\uff0c\u5426\u5219\u4e2a\u4eba\u4f1a\u9057\u81ed\u4e07\u5e74\u3001\u4e16\u754c\u8981\u906d\u5927\u52ab\u3002<\/span><\/h3>\n

\u6765\u6e90\uff1a<\/span>https:\/\/mobile.aigupiao.com\/Lives\/detail\/id\/1466116<\/span><\/a><\/p>\n

\u8fd9\u7bc7\u6587\u7ae0\u8bf4\u7684\u4e0d\u77e5\u771f\u5047<\/strong><\/span>\uff0c\u4f46\u662f\u76ee\u524d\u786e\u5b9e\u6709\u4e2a\u6700\u5927\u7684\u95ee\u9898\u6ca1\u6709\u89e3\u91ca\u660e\u767d\uff1a\u5230\u5e95\u75c5\u6bd2\u6765\u81ea\u4ec0\u4e48\u5730\u65b9\u3002\u81f3\u4eca\u4e3a\u6b62\u4e0d\u77e5\u9053\u662f\u5426\u662f\u8759\u8760\u3002\u5982\u679c\u662f\u8759\u8760\uff0c\u90a3\u4e48\u4e3a\u4ec0\u4e48\u51fa\u73b0\u5728\u6b66\u6c49\u3001\u51fa\u73b0\u5728\u75c5\u6bd2\u6240\u9644\u8fd1\u7684\u6d77\u9c9c\u5e02\u573a\u3002<\/span><\/p>\n

\"image\"<\/a><\/p>\n

\u77f3\u6b63\u4e3d\u4e8b\u4ef6\u7684\u524d\u540e\u6574\u7406\uff0c\u53ca\u6b66\u5c0f\u534e\u535a\u58eb\u6253\u8138\u5979<\/span><\/h3>\n

\u5728\u6628\u5929\uff0c\u6b66\u5c0f\u534e\u535a\u58eb\u5b9e\u540d\u6253\u8138\u77f3\u6b63\u4e3d\uff0c\u76f4\u63a5\u6307\u8d23\u8bf4\u4ed6\u4eec\u5b9e\u9a8c\u5ba4\u7ba1\u7406\u6df7\u4e71\uff0c\u5b9e\u9a8c\u7528\u7684\u52a8\u7269\u6807\u672c\u968f\u610f\u5e26\u51fa\u5f53\u5ba0\u7269\uff0c\u751a\u81f3\u628a\u6807\u672c\u9e21\u86cb\u716e\u4e86\u5403\uff01<\/span><\/p>\n

\u6765\u6e90\uff1a\u5f53\u4ee3\u6069\u683c\u65af<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\uff08\u4e00\uff09<\/span><\/p>\n

2015\u5e74\uff0c\u8457\u540d\u7684\u81ea\u7136\u533b\u5b66\u7535\u5b50\u520a\u7269\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u8bba\u6587\uff0c\u4e3b\u8981\u4f5c\u8005\u4e3a\u4e2d\u56fd\u79d1\u5b66\u9662\u6b66\u6c49\u75c5\u6bd2\u5b66\u7814\u7a76\u6240\u3001\u6b66\u6c49\u5927\u5b66\u75c5\u6bd2\u7814\u7a76\u6240\u6559\u6388\u77f3\u6b63\u4e3d\u3002<\/span><\/p>\n

\u8fd9\u7bc7\u8bba\u6587\u8bf4\uff0c\u4ed6\u4eec\u533b\u5b66\u7814\u7a76\u53d1\u73b0\uff0c\u53ea\u8981\u628a\u8759\u8760\u8eab\u4e0a\u7684S\u86cb\u767d\u91cc\u7684ACE2\u8fd9\u4e2a\u53d7\u4f53\u5f00\u5173\u4e00\u8c03\uff0c\u8fd9\u4e2a\u75c5\u6bd2\u9a6c\u4e0a\u5c31\u53ef\u4ee5\u4f20\u67d3\u7ed9\u4eba\u7c7b\u3002\u5229\u7528\u75c5\u6bd2\u57fa\u56e0\u91cd\u7ec4\u6280\u672f\u5c06\u8759\u8760\u7684S\u86cb\u767d\u548c\u5c0f\u8001\u9f20\u7684Sars\u75c5\u6bd2\u91cd\u7ec4\uff0c\u5f97\u5230\u7684\u65b0\u75c5\u6bd2\u53ef\u4ee5\u548c\u4eba\u4f53\u7684\u8840\u7ba1\u7d27\u5f20\u7d20\u8f6c\u5316\u91762\uff08ACE2\uff09\u7ed3\u5408\uff0c\u80fd\u5f88\u6709\u6548\u5730\u611f\u67d3\u4eba\u7c7b\u7684\u547c\u5438\u9053\u7ec6\u80de\uff0c\u6bd2\u6027\u5de8\u5927\u3002\u4ed6\u4eec\u53d1\u73b0\u65b0\u75c5\u6bd2\u660e\u663e\u5730\u635f\u5bb3\u4e86\u8001\u9f20\u7684\u80ba\u90e8\uff0c\u6240\u6709\u75ab\u82d7\u7ba1\u5931\u53bb\u4f5c\u7528\u3002\u4e8e\u662f\uff0c\u77f3\u6b63\u4e3d\u56e2\u961f\u7ee7\u7eed\u7528\u7334\u5b50\u505a\u5b9e\u9a8c\uff0c\u6a21\u62df\u75c5\u6bd2\u5728\u4eba\u4f53\u4e0a\u7684\u6548\u679c\u3002<\/span><\/p>\n

\u8fd9\u4e2a\u5b9e\u9a8c\u5f53\u65f6\u5f15\u8d77\u7f8e\u56fd\u533b\u5b66\u754c\u975e\u5e38\u5927\u7684\u4e89\u8bae\uff0c\u533b\u5b66\u4e13\u5bb6Declan Butler\u4e5f\u5728Nature Medicine\u4e0a\u64b0\u6587\u8868\u793a\uff0c\u8fd9\u79cd\u5b9e\u9a8c\u6ca1\u6709\u4ec0\u4e48\u610f\u4e49\uff0c\u800c\u4e14\u98ce\u9669\u5f88\u5927\u3002\u7531\u4e8e\u7f3a\u4e4f\u6280\u672f\uff0c\u5f53\u65f6\u77f3\u6b63\u4e3d\u56e2\u961f\u662f\u548c\u7f8e\u56fd\u5317\u5361\u7f57\u83b1\u7eb3\u7684\u4e00\u4e2a\u533b\u5b66\u5c0f\u7ec4\u5408\u4f5c\u3002<\/span><\/span><\/p>\n

\u8fd9\u662fDeclan Butler \u8d28\u7591\u6587\u7ae0 \uff08\u5199\u4e8e2015\u5e74\uff09\u3002<\/span><\/p>\n

engineered bat virus stirs debate over risky research<\/span><\/p>\n

\u4ee5\u4e0b\u662f\u77f3\u6b63\u4e3d\u53ca\u56e2\u961f\u53d1\u8868\u7684\u5173\u4e8e\u6539\u9020\u8759\u5e45SARS\u75c5\u6bd2\u7814\u7a76\u6587\u7ae0\u3002\uff08\u5199\u4e8e2015\u5e74\uff09<\/span><\/p>\n

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence<\/span><\/strong><\/p>\n

\u8fd9\u4e2a\u6807\u9898\u6709\u70b9\u6666\u6da9\uff0c\u662f\u4e00\u7bc7\u5d4c\u5408\u75c5\u6bd2\u7814\u7a76\uff0c<\/span><\/p>\n

\u7b80\u5355\u7ffb\u8bd1\u4e3a\uff1a<\/span><\/p>\n

\u7c7b\u4f3c\u4e8eSARS\u7684\u5faa\u73af\u8759\u8760\u51a0\u72b6\u75c5\u6bd2\u7c07\u663e\u793a\u4e86\u4eba\u7fa4\u95f4\u51fa\u73b0\u7684\u6f5c\u529b<\/span><\/strong><\/p>\n

\u5728\u8bba\u6587\u4e2d\uff0c\u8d6b\u7136\u5199\u7740\uff1a\u201c\u4e3a\u4e86\u7814\u7a76\u5faa\u73af\u8759\u8760\u51a0\u72b6\u75c5\u6bd2\u7684\u51fa\u73b0\u53ef\u80fd\u6027\uff08\u5373\u611f\u67d3\u4eba\u7c7b\u7684\u53ef\u80fd\u6027\uff09\uff0c\u6211\u4eec\u6784\u5efa\u4e86\u4e00\u79cd\u5d4c\u5408\u75c5\u6bd2\u201d\uff0c\u5e76\u8bf4\u201c\u8fd9\u79cd\u6742\u4ea4\u75c5\u6bd2\u4f7f\u6211\u4eec\u80fd\u591f\u8bc4\u4f30\u8fd9\u79cd\u65b0\u7684\u68d8\u7a81\u86cb\u767d\u5f15\u8d77\u75be\u75c5\u7684\u80fd\u529b\u3002\u201d<\/span><\/p>\n

\u4ee5\u4e0b\u662f\u8bba\u6587\u7b80\u4ecb\u7684\u4e00\u53e5\u8bdd\u53ca\u7ffb\u8bd1<\/span><\/p>\n

Using the SARS-CoV reverse genetics system2, we generated and characterized a chimeric virus expssing the spike of bat coronavirus SHC014 in a mouse-adapted SARS-CoV backbone.<\/span><\/p>\n

\u8c37\u6b4c\u76f4\u8bd1\u4e3a\uff1a\u4f7f\u7528SARS-CoV\u53cd\u5411\u9057\u4f20\u5b66\u7cfb\u7edf2\uff0c\u6211\u4eec\u751f\u6210\u5e76\u9274\u5b9a\u4e86\u4e00\u79cd\u5728\u9002\u5e94\u5c0f\u9f20\u7684SARS-CoV\u4e3b\u5e72\u4e2d\u8868\u8fbe\u8759\u8760\u51a0\u72b6\u75c5\u6bd2SHC014\u7684\u5c16\u5cf0\u7684\u5d4c\u5408\u75c5\u6bd2\u3002<\/strong><\/span><\/span><\/p>\n

2014\u5e74\u7f8e\u56fd\u75be\u75c5\u63a7\u5236\u4e2d\u5fc3\u610f\u8bc6\u5230\u8fd9\u4e2a\u75c5\u6bd2\u6709\u53ef\u80fd\u6210\u4e3a\u751f\u7269\u5316\u5b66\u6b66\u5668\u65f6\uff0c\u7acb\u523b\u5df2\u7ecf\u53eb\u505c\u4e86\u8fd9\u79cd\u75c5\u6bd2\u6539\u9020\u8ba1\u5212\uff0c\u5e76\u505c\u6b62\u62e8\u6b3e\u7ed9\u76f8\u5173\u7684\u7814\u7a76\u3002<\/span><\/p>\n

\uff08\u7b14\u8005\u5f88\u597d\u5947\u4ed6\u4eec\u662f\u5982\u4f55\u5728\u6700\u521d\u9a97\u5230\u7814\u7a76\u7ecf\u8d39\u7684\uff0c\u5988\u768421\u4e16\u7eaa\u679c\u7136\u662f\u751f\u7269\u7684\u4e16\u7eaa\uff09<\/span><\/strong><\/p>\n

\uff08\u4e8c\uff09<\/span><\/strong><\/p>\n

\u7531\u4e8e\u4e00\u4e9b\u8c23\u8a00\u7684\u51fa\u73b0\uff0c<\/strong>\u77f3\u6b63\u4e3d\u5973\u58eb\u6700\u8fd1\u53d1\u670b\u53cb\u5708\u8fdb\u884c\u4e86\u9a73\u65a5\uff1a<\/strong><\/span><\/span><\/p>\n

\"image\"<\/a><\/p>\n

\uff08\u4e09\uff09<\/span><\/p>\n

\u5728\u6628\u5929\uff0c\u6b66\u5c0f\u534e\u535a\u58eb\u5b9e\u540d\u6253\u8138\u77f3\u6b63\u4e3d\uff0c\u76f4\u63a5\u6307\u8d23\u8bf4\u4ed6\u4eec\u5b9e\u9a8c\u5ba4\u7ba1\u7406\u6df7\u4e71\uff0c\u5b9e\u9a8c\u7528\u7684\u52a8\u7269\u6807\u672c\u968f\u610f\u5e26\u51fa\u5f53\u5ba0\u7269\uff0c\u751a\u81f3\u628a\u6807\u672c\u9e21\u86cb\u716e\u4e86\u5403\uff01<\/span><\/strong><\/p>\n

\u4ee5\u4e0b\u662f\u6b66\u535a\u58eb\u6388\u6743\u7684\u6587\u5b57\uff1a<\/span><\/strong><\/p>\n

\n

\u201c\u5728\u4ec0\u4e48\u60c5\u51b5\u4e0b\u624d\u80fd\u6253\u901a\u5927\u9f20\u548c\u7075\u957f\u7c7b\u5462?\u90a3\u5c31\u662f\u628a\u7075\u957f\u7c7b\u7684\u67d0\u4e2a\u86cb\u767d\uff0c\u6539\u9020\u5728\u5927\u9f20.\u4e0a\u3002<\/span><\/em><\/p>\n

\u8fd9\u4e2a\u53ea\u6709\u5728\u5b9e\u9a8c\u5ba4\u624d\u80fd\u5b8c\u6210\u7684\u6539\u9020\u5e76\u4e0d\u590d\u6742\u6280\u672f\u4e5f\u5f88\u6210\u719f\uff0c\u800c\u4e14\u975e\u5e38\u975e\u5e38\u591a\u7684\u7528\u5728\u836f\u7269\u5b9e\u9a8c\u4e0a\u3002<\/em>\u5148\u53ea\u8981\u67e5\u4e00\u4e0b\u77f3\u7814\u7a76\u5458\u7684\u5b9e\u9a8c\u52a8\u7269\u8d44\u6599\u6709\u6ca1\u6709\u5927\u9f20\u548c\u7075\u957f\u7c7b\u53c2\u4e0e\u5c31\u53ef\u4ee5\u7834\u89e3\u4e86\u3002<\/em><\/span><\/span><\/strong><\/p>\n

\u5176\u6b21\uff0c\u5b9e\u9a8c\u5ba4\u662f\u600e\u4e48\u53d1\u751f\u751f\u7269\u6cc4\u9732\u7684\uff0c\u8fd9\u5c31\u662f\u7ba1\u7406\u7684\u95ee\u9898\u4e86\u3002<\/em><\/span><\/span><\/p>\n

\u6709\u4e9b\u5b9e\u9a8c\u5ba4\u975e\u5e38\u7cdf\u7cd5\uff0c\u5411\u5916\u515c\u552e\u53c2\u4e0e\u5b9e\u9a8c\u7684\u5b9e\u9a8c\u52a8\u7269,\u6bd4\u5982\u72d7\u5f53\u5ba0\u7269(\u534f\u548c\u533b\u5b66\u9662\u5c31\u5e72\u8fc7\u8fd9\u4e8b\uff0c\u800c\u4e14\u56e0\u4e3a\u5b9e\u9a8c\u52a8\u7269\u6bd4\u6d41\u6d6a\u732b\u72d7\u66f4\u53ef\u601c\uff0c\u6240\u4ee5\u6bcf\u5e74\u670b\u53cb\u90fd\u4f1a\u88ab\u6211\u529d\u7740\u6536\u517b\u4e00\u4e24\u53ea\uff0c\u62c9\u5e03\u62c9\u591a\u548c\u957f\u8033\u6735\u7684\u90a3\u79cd\u72d7\u6700\u591a)\u3002<\/em><\/span><\/span><\/p>\n

\u8fd8\u6709\u628a\u628a\u5b9e\u9a8c\u52a8\u7269\u7684\u5c38\u4f53\u968f\u4fbf\u5904\u7406\uff0c\u56e0\u4e3a\u6309\u7167\u533b\u7597\u5e9f\u7269\u706b\u846c\u94b1\u66f4\u591a\uff0c\u66f4\u6709\u6309\u91ce\u751f\u52a8\u7269\u552e\u5356\u7684(\u95ee\u95ee\u5357\u65b9\u533b\u79d1\u5927\u5b66\u6709\u6ca1\u6709\u5356\u8fc7\u7315\u7334\u5427)\u3002<\/em><\/span><\/span><\/p>\n

\u5b9e\u9a8c\u5ba4\u7684SPF\u9e21\u86cb\u968f\u4fbf\u716e\u7740\u5403\u7684\uff0c\u8fd9\u4e2a\u662f\u67d0\u6b21\u6211\u9001\u8fc7\u53bb\u7684\u6570\u91cf\u5c11\u4e86\uff0c\u7136\u540e\u5c31\u6df1\u67e5\uff0c\u7ed3\u679c\u4e24\u4e2a\u5b66\u751f\u8bf4\u8fd8\u5269\u4e0b\u662f\u4e2a\u4ed6\u4eec\u665a\u4e0a\u503c\u73ed\u997f\u4e86\u716e\u7740\u5403\u4e86\u8fd9\u4e2a\u9e21\u86cb\u6ca1\u53c2\u4e0e\u5b9e\u9a8c\u5f53\u7136\u80fd\u5403\u800c\u4e14\u5f88\u7f8e\u5473\u3002<\/em><\/span><\/span><\/p>\n

\u5b9e\u9a8c\u5ba4\u7684\u732a\u5206\u4e86\u5403\u7684(\u4f60\u95ee\u95ee\u4f60\u4eec301\u533b\u9662\u9aa8\u79d1\u505a\u810a\u690e\u5916\u79d1\u5b9e\u9a8c\u7684\u732a\u54ea\u91cc\u53bb\u4e86\u5c31\u77e5\u9053\u4e86)\u3002<\/strong><\/em><\/span><\/span><\/p>\n

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\u5404\u79cd\u6df7\u4e71\uff0c\u4e5f\u8bb8\u75c5\u6bd2\u7684\u53d8\u5f02\u5c5e\u4e8e\u5076\u5408\u3001\u5de7\u5408\u3001\u6216\u8005\u5b9e\u9a8c\u610f\u5916\uff0c\u4f46\u662f\u5b9e\u9a8c\u5ba4\u7684\u7ba1\u7406\u771f\u7684\u6ca1\u95ee\u9898\u5417?\u5475\u5475\u3002<\/span><\/em><\/p>\n

\u77f3\u7814\u7a76\u5458\uff0c\u8bf7\u95ee\u4f60<\/em>– -\u6761\u547d\u548c\u51e0\u767e\u6761\u4eba\u547d\u76f8\u6bd4\uff0c\u90a3\u4e2a\u66f4\u9e3f\u6bdb\u90a3\u4e2a\u66f4\u6cf0\u5c71\uff1f<\/em><\/span><\/span><\/p>\n

\u6211\u672c\u4ee5\u4e3a\u60a8\u6d88\u5931\u4e86\uff0c\u6ca1\u60f3\u5230\u4f60\u51fa\u6765\u9a82\u8857\u4e86\uff0c\u6765\u6765\u6765\uff0c\u6211\u4e0d\u9020\u8c23\u4e5f\u4e0d\u8f9f\u8c23\uff0c\u4f46\u6211\u4e5f\u4e0d\u662f\u5403\u5e72\u996d\u7684\uff0c\u73b0\u5728\u4f60\u8bba\u6587\u516c\u5e03\u7684\u5b9e\u9a8c\u6570\u636e\u548cCDC\u7684\u57fa\u56e0\u5bf9\u6bd4\uff0c\u8fd9\u4e2d\u95f4\u5982\u679c\u6ca1\u6709SPF\u52a8\u7269\u505a\u4e3a\u4e2d\u95f4\u5bbf\u4e3b\uff0c\u4f1a\u53d1\u751f\u8fd9\u6837\u7684\u53d8\u5f02?<\/span><\/em><\/p>\n

\u6211\u628a\u8bdd\u6482\u8fd9\u91cc\uff0c\u54b1\u4eec\u53ef\u4ee5\u516c\u5f00\u5bf9\u8d28\uff0c\u6211\u770b\u4f60\u80fd\u7cca\u5f04\u51e0\u4e2a\u4eba!\u672c\u4eba\u4eb2\u81ea\u517b\u8fc7SPF\u52a8\u7269\uff0c\u4e5f\u505a\u8fc7SPF\u57fa\u56e0\u5b9e\u9a8c\uff0c\u4f60\u4e0d\u8981\u628a\u5927\u5bb6\u5f53\u767d\u75f4\uff01<\/em>\u6b22\u8fce\u8f6c\u53d1\u3002\u201d<\/em><\/span><\/span><\/p>\n

\n

\u5bf9\u4e8e\u77f3\u535a\u58eb\u548c\u6b66\u535a\u58eb\u7684\u4e89\u8bba\uff0c\u7ad9\u7740\u4e2d\u7acb\u7684\u89c2\u70b9\uff0c\u6211\u4eec\u4ec0\u4e48\u4e5f\u4e0d\u77e5\u9053\u3002<\/span><\/strong><\/p>\n

\u00a0<\/span><\/strong><\/p>\n

\uff08\u56db\uff09<\/span><\/p>\n

\u9644\u6587\uff1a<\/span><\/p>\n

\u77f3\u6b63\u4e3d\u4e2a\u4eba\u7b80\u5386<\/span><\/strong><\/p>\n

\u77f3\u6b63\u4e3d\uff0c\u7814\u7a76\u5458\uff0c\u535a\u58eb\u751f\u5bfc\u5e08\u3002\u73b0\u4e3a\u4e2d\u79d1\u9662\u65b0\u53d1\u548c\u70c8\u6027\u75c5\u539f\u4e0e\u751f\u7269\u5b89\u5168\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u4e3b\u4efb\u3001\u6b66\u6c49\u75c5\u6bd2\u6240\u65b0\u53d1\u4f20\u67d3\u75c5\u7814\u7a76\u4e2d\u5fc3\u4e3b\u4efb\u3001\u6b66\u6c49\u56fd\u5bb6\u9ad8\u7b49\u7ea7\u751f\u7269\u5b89\u5168\u5b9e\u9a8c\u5ba4\uff08P4\uff09\u526f\u4e3b\u4efb\u548c\u751f\u7269\u5b89\u51683\u7ea7\u5b9e\u9a8c\u5ba4\u4e3b\u4efb\u3002<\/span><\/p>\n

\"image\"<\/a><\/p>\n

\u73b0\u4efb\u300a\u75c5\u6bd2\u5b66\u62a5\u300b\u7f16\u59d4\u3001\u300a\u4e2d\u56fd\u75c5\u6bd2\u5b66\u300b\u7f16\u59d4\uff1b\u4e2d\u56fd\u5fae\u751f\u7269\u5b66\u4f1a\u75c5\u6bd2\u4e13\u4e1a\u59d4\u5458\u4f1a\u59d4\u5458\u3002<\/span><\/p>\n

\u77f3\u6b63\u4e3d\u7814\u7a76\u54581987\u5e747\u6708\u6bd5\u4e1a\u4e8e\u6b66\u6c49\u5927\u5b66\u751f\u7269\u7cfb\u9057\u4f20\u4e13\u4e1a\uff0c\u83b7\u5b66\u58eb\u5b66\u4f4d\u30021990\u5e747\u6708\u6bd5\u4e1a\u4e8e\u4e2d\u79d1\u9662\u6b66\u6c49\u75c5\u6bd2\u6240\uff0c\u83b7\u7855\u58eb\u5b66\u4f4d\u30022000\u5e745\u6708\u83b7\u6cd5\u56fd\u8499\u5f7c\u5229\u57c3\uff08Montpellier\uff09\u7b2c\u4e8c\u5927\u5b66\u535a\u58eb\u5b66\u4f4d\u3002\u957f\u671f\u4ece\u4e8b\u65b0\u53d1\u75c5\u6bd2\u7684\u7814\u7a76\uff0c\u5728\u75c5\u6bd2\u7684\u5206\u79bb\u548c\u9274\u5b9a\u3001\u75c5\u6bd2\u7684\u9057\u4f20\u8fdb\u5316\u3001\u75c5\u6bd2\u7684\u68c0\u6d4b\u6280\u672f\u3001\u75c5\u6bd2\u7684\u5206\u5b50\u6d41\u884c\u75c5\u5b66\u7b49\u65b9\u9762\u6709\u957f\u671f\u7684\u79ef\u7d2f\u548c\u7814\u7a76\u7ecf\u9a8c\u3002<\/span><\/p>\n

\u4e3b\u8981\u8d21\u732e\u6709\uff1a\u5728\u8759\u8760\u4f53\u5185\u53d1\u73b0\u9057\u4f20\u591a\u6837\u7684SARS\u6837\u51a0\u72b6\u75c5\u6bd2\uff0c\u5e76\u9996\u6b21\u6210\u529f\u5206\u79bb\u5230\u4e0eSARS\u75c5\u6bd2\u9ad8\u5ea6\u540c\u6e90\u7684\u8759\u8760\u51a0\u72b6\u75c5\u6bd2\uff0c\u8bc1\u660e\u8759\u8760\u662fSARS\u51a0\u72b6\u75c5\u6bd2\u7684\u81ea\u7136\u5bbf\u4e3b\uff0c\u63ed\u793a\u4e86SARS\u75c5\u6bd2\u4ece\u8759\u8760\u5230\u4eba\u7684\u751f\u6001\u4f20\u64ad\u94fe(Science, 2005; Nature, 2013)\uff1b\u5728\u6211\u56fd\u8759\u8760\u4f53\u5185\u68c0\u6d4b\u5230\u70c8\u6027\u75c5\u6bd2\u5c3c\u5e15\u75c5\u6bd2\u548c\u57c3\u535a\u62c9\u75c5\u6bd2\u7684\u6297\u4f53\uff0c\u4e3a\u8759\u8760\u75c5\u6bd2\u5f15\u8d77\u7684\u70c8\u6027\u65b0\u53d1\u4f20\u67d3\u75c5\u7684\u9884\u9632\u63d0\u4f9b\u4e86\u9884\u8b66\u7b56\u7565(Emerging Infectious Disease , 2008; Virology Journal, 2012)\uff1b\u9996\u6b21\u89e3\u6790\u4e862\u79cd\u8759\u8760\u7684\u57fa\u56e0\u7ec4\u5e8f\u5217\uff0c\u63d0\u793a\u8759\u8760\u5177\u6709\u72ec\u7279\u7684<\/span>\u6297\u75c5\u6bd2<\/span><\/a>\u514d\u75ab\u7279\u5f81\uff0c\u4e3a\u540e\u7eed\u7814\u7a76\u8759\u8760<\/span>\u6297\u75c5\u6bd2<\/span><\/a>\u514d\u75ab\u673a\u5236\u63d0\u4f9b\u4e86\u57fa\u7840(Science , 2013)\uff1b\u5728\u8759\u8760\u4f53\u5185\u68c0\u6d4b\u5230\u9057\u4f20\u591a\u6837\u7684\u817a\u75c5\u6bd2\u3001\u817a\u76f8\u5173\u75c5\u6bd2\u548c\u5706\u73af\u75c5\u6bd2\uff0c\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u8759\u8760\u662f\u591a\u79cd\u75c5\u6bd2\u7684\u81ea\u7136\u5bbf\u4e3b\uff08Journal of Virology, 2010; Journal of General Virology, 2010\u548c2011\uff09\u3002<\/span><\/p>\n

\u76ee\u524d\u627f\u62c5\u6709\u56fd\u5bb6973\u3001\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u91cd\u5927\u9879\u76ee\u7b49\u8bfe\u9898\u3002<\/span><\/p>\n

\u00a0<\/span><\/p>\n

<\/i>\u70b9\u8d5e(1246<\/em>)<\/span><\/a><\/p>\n

\u5206\u4eab\u81f3\uff1a<\/span><\/p>\n

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<\/span><\/p>\n

\u8bf7 <\/span>\u767b\u5f55<\/span><\/a> \u53c2\u4e0e\u8ba8\u8bba<\/span><\/p>\n

\u5168\u90e8\u8bc4\u8bba(112)<\/span><\/a><\/p>\n